Tn5 synaptic complex formation: role of transposase residue W450.
نویسندگان
چکیده
A series of Tn5 transposases (Tnp's) with mutations at the conserved amino acid position W450, which was structurally predicted to be important for synapsis, have been generated and characterized. This study demonstrates that W450 is involved in hydrophobic (and possibly aromatic) contacts within the Tnp monomer that negatively regulate synaptic complex formation.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 190 4 شماره
صفحات -
تاریخ انتشار 2008